Squaraine as a bright, stable and environment-sensitive far-red label for receptor-specific cellular imaging
Squaraine as a bright, stable and environment-sensitive far-red label for receptor-specific cellular imaging
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DOI：
10.1039/c4cc09113b
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发表时间：
2015-01-01
影响因子：
4.9
通讯作者：
Bonnet, D.
中科院分区：
文献类型：
--
作者：
Karpenko, I. A.;Klymchenko, A. S.;Bonnet, D.
在这里，我们表明，远红的芳叉方酸染料是稳定的亲核试剂，在对比芳-方酸。由于该染料在非极性介质中的荧光增强以及高亮度和光稳定性，该染料被成功地应用于检测催产素G蛋白偶联受体并监测其在活细胞中的内化。
Herein, we show that a far-red arylidene-squaraine dye is stable against nucleophiles, in contrast to arene-squaraines. Owing to the fluorescence enhancement in apolar media together with high brightness and photostability, this dye was successfully applied to detect the oxytocin G protein-coupled receptor and monitor its internalization in living cells.