Ventricular Volume of Nonbeating Excised Dog Hearts in the State of Elastic Equilibrium
Ventricular Volume of Nonbeating Excised Dog Hearts in the State of Elastic Equilibrium
复制标题
弹性平衡状态下无搏动离体狗心脏的心室容积
DOI：
10.1161/01.res.19.6.1080
复制
发表时间：
1966
影响因子：
20.1
通讯作者：
A. D. Horres
中科院分区：
文献类型：
--
作者：
G. A. Brecher;H. Kolder;A. D. Horres
左心室和右心室的容积从心室处于弹性平衡状态时的零跨壁压开始至30 mm Hg的负跨壁压进行静态测量。将新鲜切除的狗心脏浸没在10°C的林格氏溶液中以建立零跨壁压，以抵消心室壁重量对心室形状的贡献，并延迟死后变化的发生。通过一个方程近似计算体积，该方程包括体重的幂函数和心室重量的幂函数。对于雄性犬，当处于弹性平衡状态时，体重为10 kg，心室重量为58 g时，左心室的平均体积为14.5 ml;右心室的相应数值为12.2 ml。在低于一定心室容积的静止心脏中，势能将存储在心室壁的结构元件中，这将促进心室的填充。
The volume in the left ventricle and that in the right ventricle were measured statically starting from zero transmural pressure, when the ventricle is in the state of elastic equilibrium, to a negative transmural pressure of 30 mm Hg. Freshly excised dog hearts were submerged in Ringer's solution at 10°C to establish zero transmural pressure, to offset the contribution of the weight of the ventricular walls on the shape of the ventricle, and to retard the onset of postmortem changes. The volume was approximated by an equation which included a power function of the body weight and another of the ventricular weight. For male dogs, the left ventricle when in the state of elastic equilibrium contained a mean volume of 14.5 ml for a body weight of 10 kg and a ventricular weight of 58 g; the corresponding figure for the right ventricle was 12.2 ml. In a quiescent heart below a certain ventricular volume, potential energy will be stored in structural elements of the ventricle wall that will facilitate the filling of the ventricle.