Integrated lung field segmentation of injured region with anatomical structure analysis by failure-recovery algorithm from chest CT images
Integrated lung field segmentation of injured region with anatomical structure analysis by failure-recovery algorithm from chest CT images
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DOI：
10.1016/j.bspc.2013.10.005
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发表时间：
2014-07-01
影响因子：
5.1
通讯作者：
Guerra Tsuzuki, Marcos de Sales
中科院分区：
文献类型：
--
作者：
Lwao, Yuma;Gotoh, Toshiyuki;Guerra Tsuzuki, Marcos de Sales
这项工作提出了一种基于计算机断层扫描（CT）的弥漫性肺部疾病诊断的功能，可以从肺部解剖结构对疾病进行评估。提出了一种自动分割胸部CT解剖结构的方法：肺叶、气道树和肺血管树。使用故障跟踪和恢复算法对气道和肺血管树进行分割。该算法检查中间结果的一致性，如果检测到故障，则返回到历史位置。结果的质量得到改善，同时减少了处理时间，即使是患有肺部疾病的受试者。采用相同的算法分割不同种子点的肺血管。气管树分割的种子在气管管内，肺血管分割的种子在心脏内。该算法通过从四种不同类型的受试者获得的CT图像进行测试：健康，特发性间质性肺炎（iip），通常间质性肺炎（UIP）和慢性阻塞性肺疾病（COPD）。在分节气道中发现主支气管，并确定相关的肺叶。结合肺叶分段和肺弥漫性疾病分类，可以量化肺叶损伤的程度和部位。结果与传统的三维区域生长算法和商业系统进行了比较。有几个结果与医生的评估进行了比较：肺叶间裂、肺叶受伤百分比以及肺和肺叶体积。所提出的算法被评估为具有足够的鲁棒性来分割所研究的案例。(C) 2013 Elsevier Ltd.版权所有。
This work proposes a functionality for computerized tomography (CT) based investigation of diffuse lung diseases diagnosis that enables the evaluation of the disease from lung anatomical structures. Automated methods for segmenting several anatomy structures in chest CT are proposed: namely the lobe lungs, airway tree and pulmonary vessel tree. The airway and pulmonary vessel trees are segmented using a failure tracking and recovery algorithm. The algorithm checks intermediary results consistence, backtrack to a history position if a failure is detected. The quality of the result is improved while reducing the processing time even for subjects with lung diseases. The pulmonary vessels are segmented through the same algorithm with different seed points. The seed for the airway tree segmentation is within the tracheal tube, and the seed for the pulmonary vessels segmentation is within the heart. The algorithm is tested with CT images acquired from four distinct types of subjects: healthy, idiopathic interstitial pneumonias (IIPs), usual interstitial pneumonia (UIP) and chronic obstructive pulmonary disease (COPD). The main bronchi are found in the segmented airway and the associated lung lobes are determined. Combining the segmented lung lobes and the diffuse lung diseases classification, it is possible to quantify how much and where each lobe is injured. The results were compared with a conventional 3D region growing algorithm and commercial systems. Several results were compared to medical doctor evaluations: interlobe fissure, percentage of lung lobe that is injured and lung and lobe volumes. The algorithm proposed was evaluated to be robust enough to segment the cases studied. (C) 2013 Elsevier Ltd. All rights reserved.