Do Exercise Trials for Hypertension Adequately Report Interventions? A Reporting Quality Study
Do Exercise Trials for Hypertension Adequately Report Interventions? A Reporting Quality Study
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DOI：
10.1055/a-0649-1040
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发表时间：
2018-11-01
影响因子：
2.5
通讯作者：
Weisser, Burkhard
中科院分区：
文献类型：
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作者：
Hacke, Claudia;Nunan, David;Weisser, Burkhard
非药物治疗，包括运动，是高血压患者的重要治疗选择。该研究评估了关于该主题的最新荟萃分析中基于运动的干预措施的报告质量，以评估研究结果在临床实践中的可转移性。采用TIDieR（干预描述和复制模板）和CERT（运动报告模板共识）指南，对1195名高血压患者耐力训练降血压效果的meta分析中24项随机对照试验的报告质量进行了评估。研究了出版期刊的报告质量、出版年份和影响因子之间的关系。没有一项研究完全描述了所有的干预成分。平均61% (95% CI: 52-69) （TIDieR）和57% (95% CI: 49-64) （CERT）报告了复制所需的核心项目。常见的缺点是对依从性、干预提供者和不良事件的报告。22%的患者缺少运动剂量的详细信息（95% CI: 4-40）。发表年份与TIDieR依从性相关（r = 0.549, P = 0.007），但与CERT无关。与期刊影响因子无关联。以运动为基础的高血压干预的报告不足以允许复制，并且限制了证据转化为临床实践。研究人员应该申请，评论作者、期刊编辑和审稿人应该检查报告指南的遵守情况。
Non-pharmacological treatment, including exercise, is an important therapy option for patients with hypertension. The study assessed the reporting quality of exercise-based interventions included in the latest meta-analysis on that topic in order to evaluate the transferability of findings into clinical practice. Reporting quality of 24 randomised controlled trials from a meta-analysis assessing blood pressure lowering effects of endurance training in 1,195 hypertensive patients was evaluated using TIDieR (Template for Intervention Description and Replication) and CERT (Consensus on Exercise Reporting Template) guidelines. Associations between reporting quality, publication year and impact factor of the publishing journals were examined. None of the studies described all intervention components completely. On average 61 % (95 % CI: 52-69) (TIDieR) and 57 % (95 % CI: 49-64) (CERT) of core items required for replication were reported. Frequent shortcomings were the reporting of adherence, intervention provider, and adverse events. Details about exercise dosage were missing in 22 % (95 % CI: 4-40). Publication year was related to the adherence to TIDieR (r = 0.549, P = 0.007) but not to CERT. No associations with journal impact factor were found. Reporting of exercisebased interventions for hypertension is not sufficient to allow for replication and limits translation of evidence into clinical practice. Researchers should apply, and review authors, journal editors and reviewers should check adherence to reporting guidelines.