Pregnancy outcome and prepregnancy body mass index in 2459 glucose-tolerant Danish women

Pregnancy outcome and prepregnancy body mass index in 2459 glucose-tolerant Danish women
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DOI:
10.1067/mob.2003.441
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发表时间:
2003-07-01
影响因子:
9.8
通讯作者:
Beck-Nielsen, H
Beck-Nielsen, H
中科院分区:
医学1区
文献类型:
--
作者:
Jensen, DM;Damm, P;Beck-Nielsen, H

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目的:本研究旨在探讨妊娠结局和孕前超重或肥胖的妇女与正常的葡萄糖耐量test.Study设计:一个历史队列研究的2459名孕妇进行系统检查妊娠期糖尿病之间的关系。从病历中收集口服葡萄糖耐量试验结果和临床结局的信息。高血压并发症的风险,剖腹产,在超重妇女中,(体重指数[BMI] 25.0-29.9 kg/m2)和肥胖女性(BMI大于或等于30.0 kg/m(2))与正常体重的女性(BMI 18.5-24.9 kg/m(2))相比。肩难产,早产,婴儿发病率以外的巨大儿的频率与产妇BMI.CONCLUSION:孕前超重和肥胖与不良妊娠结局的葡萄糖耐受的妇女。
OBJECTIVE: This study was undertaken to investigate the relationship between pregnancy outcome and prepregnancy overweight or obesity in women with a normal glucose tolerance test.STUDY DESIGN: A historical cohort study of 2459 pregnant women systematically examined for gestational diabetes was performed. Information of oral glucose tolerance test results and clinical outcome were collected from medical records.RESULTS: The risk of hypertensive complications, cesarean section, induction of labor and macrosomia was significantly increased in both overweight women (body mass index [BMI] 25.0-29.9 kg/m(2)) and obese women (BMI greater than or equal to 30.0 kg/m(2)) compared with women who were of normal weight (BMI 18.5-24.9 kg/m(2)). The frequencies of shoulder dystocia, preterm delivery, and infant morbidity other than macrosomia were not significantly associated with maternal BMI.CONCLUSION: Prepregnancy overweight and obesity is associated with adverse pregnancy outcome in glucose-tolerant women.