Triflumezopyrim: Discovery and Optimization of a Mesoionic Insecticide for Rice
Triflumezopyrim: Discovery and Optimization of a Mesoionic Insecticide for Rice
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DOI：
10.1021/bk-2015-1204.ch026
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发表时间：
2015
期刊：
影响因子：
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通讯作者：
C. Holyoke;Wenming Zhang;Thomas F Pahutski;G. Lahm;M. T. Tong;D. Cordova;M. E. Schroeder;E. Benner
中科院分区：
文献类型：
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作者：
C. Holyoke;Wenming Zhang;Thomas F Pahutski;G. Lahm;M. T. Tong;D. Cordova;M. E. Schroeder;E. Benner
三氟嘧啶是一种非常有效的飞虱杀虫剂，对包括传粉昆虫在内的非目标生物的影响很小。这类独特的介离子化学靶向烟碱乙酰胆碱受体，诱导不同于新烟碱类的生理作用。讨论了其发现、合成、优化和作用方式。
Triflumezopyrim is an extremely effective hopper insecticide with low impact on non-target organisms including pollinators. This unique class of mesoionic chemistry targets the nicotinic acetylcholine receptor , inducing a physiological action which is distinct from that of neonicotinoids. The discovery, synthesis, optimization and mode of action will be discussed.