Diabetes, Pancreatogenic Diabetes, and Pancreatic Cancer.
Diabetes, Pancreatogenic Diabetes, and Pancreatic Cancer.
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DOI：
10.2337/db16-1477
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发表时间：
2017-05
期刊：
影响因子：
7.7
通讯作者：
Abbruzzese JL
中科院分区：
文献类型：
--
作者：
Andersen DK;Korc M;Petersen GM;Eibl G;Li D;Rickels MR;Chari ST;Abbruzzese JL
糖尿病与胰腺导管腺癌（PDAC）之间的关系是复杂的。长期存在的2型糖尿病（T2DM）是胰腺癌的一个危险因素，但越来越多的流行病学数据表明，PDAC也是糖尿病的一个原因，原因尚不清楚。新发糖尿病是肿瘤学界特别关注的问题，因为PDAC引起的新发糖尿病与T2DM不同，可以更早诊断PDAC。为了解决这些关系并提高对PDAC和糖尿病之间关系的认识，2016年6月在美国糖尿病协会第76届科学会议上举行了题为糖尿病，胰源性糖尿病和胰腺癌的研讨会。本文总结了该研讨会上提出的数据，描述了目前对糖尿病，糖尿病管理和胰腺癌之间相互关系的理解，并确定了需要进一步研究的领域。
The relationships between diabetes and pancreatic ductal adenocarcinoma (PDAC) are complex. Longstanding type 2 diabetes (T2DM) is a risk factor for pancreatic cancer, but increasing epidemiological data point to PDAC as also a cause of diabetes due to unknown mechanisms. New-onset diabetes is of particular interest to the oncology community as the differentiation of new-onset diabetes caused by PDAC as distinct from T2DM may allow for earlier diagnosis of PDAC. To address these relationships and raise awareness of the relationships between PDAC and diabetes, a symposium entitled Diabetes, Pancreatogenic Diabetes, and Pancreatic Cancer was held at the American Diabetes Association’s 76th Scientific Sessions in June 2016. This article summarizes the data presented at that symposium, describing the current understanding of the interrelationships between diabetes, diabetes management, and pancreatic cancer, and identifies areas where additional research is needed.