Design and synthesis of intrinsically cell-penetrating nucleopeptides
Design and synthesis of intrinsically cell-penetrating nucleopeptides
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DOI：
10.1039/b811639c
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发表时间：
2008-10-21
影响因子：
3.2
通讯作者：
Bianco, Alberto
中科院分区：
文献类型：
--
作者：
Geotti-Bianchini, Piero;Beyrath, Julien;Bianco, Alberto
由在其侧链上带有核碱基的α-氨基酸构成的核肽能够渗透到细胞中并到达细胞核而没有细胞毒性作用。
Nucleopeptides, which are constituted of a-amino acids bearing nucleobases at their side chains, are able to penetrate into cells and to reach the nucleus without cytotoxic effects.