Plasma gonadotropins, prolactin, gonadal steroids, and genital swelling during the menstrual cycle of lowland gorillas.
Plasma gonadotropins, prolactin, gonadal steroids, and genital swelling during the menstrual cycle of lowland gorillas.
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低地大猩猩月经周期中的血浆促性腺激素、催乳素、性腺类固醇和生殖器肿胀。
DOI：
10.1210/endo-105-1-290
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发表时间：
1979
期刊：
影响因子：
4.8
通讯作者：
Kenneth G. Gould
中科院分区：
文献类型：
--
作者：
Ronald D. Nadler;Charles E. Graham;Delwood C. Collins;Kenneth G. Gould
在三只大猩猩的四个月经周期中测量了血浆LH、FSH、PRL、17β-雌二醇、孕酮和睾酮，并评估了它们与生殖器肿胀（阴唇肿胀）的关系，作为对灵长类生殖生理学比较观点的贡献。周期长度变化很大（23-48天），但黄体期的长度相对恒定（11-13天）。所有周期均显示周期中期LH峰值（25.9-48.1 mIU/ml）和黄体期孕酮升高（10.8-12.2 ng/ml），提示排卵功能正常。FSH在周期中期增加，但不像LH那样一致。PRL无节律性。17β-雌二醇在黄体生成素峰值之前出现中期升高（200-500 pg/ml），黄体期升高与孕酮的时间进程接近。在卵泡期几乎检测不到孕酮（<0.5 ng/ml），在LH峰值当天（n = 2）或一天后（n = 2）升高，在LH峰值后6-7天达到峰值，然后降至低水平。
Plasma LH, FSH, PRL, 17β-estradiol, progesterone, and testosterone were measured during four menstrual cycles in three gorillas, and their relationship to genital swelling (labial tumescence) was assessed as a contribution to the comparative perspective on primate reproductive physiology. Cycle length varied considerably (23–48 days), but the length of the luteal phase was relatively constant (11–13 days). All cycles exhibited a midcycle LH peak (25.9–48.1 mIU/ml) and a luteal phase elevation in progesterone (10.8–12.2 ng/ml), suggesting normal ovulatory function. FSH increased at midcycle but not as consistently as LH. PRL showed no rhythmicity. 17β-Estradiol showed a midcycle elevation (200–500 pg/ml) that preceded the LH peak and a luteal phase elevation that approximated the time course of progesterone. Progesterone was barely detectable during the follicular phase (<0.5 ng/ml), rose on the day of the LH peak (n = 2) or a day later (n = 2), peaked 6–7 days after the LH peak, and decreased to low level...