The Relationship between Characteristics of Inguinal Lymph Nodes and Pelvic Lymph Node Involvement in Penile Squamous Cell Carcinoma: A Single Institution Experience
The Relationship between Characteristics of Inguinal Lymph Nodes and Pelvic Lymph Node Involvement in Penile Squamous Cell Carcinoma: A Single Institution Experience
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DOI：
10.1016/j.juro.2013.10.140
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发表时间：
2014-04-01
影响因子：
6.6
通讯作者：
Nicolai, Nicola
中科院分区：
文献类型：
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作者：
Lughezzani, Giovanni;Catanzaro, Mario;Nicolai, Nicola
目的：探讨阴茎癌患者盆腔淋巴结转移的预测因素。材料与方法：共收集142例阴茎癌患者的188个腹股沟淋巴结阳性标本。Logistic回归模型用于检验盆腔淋巴结转移的预测因素。结果：盆腔淋巴结转移45例(31.7%)。腹股沟和盆腔淋巴结转移者的5年生存率分别为71.0%和33.2%。最显著的临界值是3个腹股沟淋巴结转移，转移直径为30 mm。根据单因素Logistic回归模型，腹股沟转移灶个数的OR1.92，p
Purpose: We determined predictors of pelvic lymph node metastases in patients with penile cancer.Materials and Methods: We retrieved a total of 188 node positive inguinal groins from 142 patients treated for penile cancer. Logistic regression models were fitted to test for predictors of pelvic lymph node metastases. The minimum p value method was used to determine the most significant cutoff values of each predictor.Results: Pelvic lymph node metastases were observed in 45 cases (31.7%). The 5-year cancer specific survival rate was 71.0% vs 33.2% in patients with inguinal vs pelvic lymph node metastases. The most significant cutoff values were 3 inguinal lymph node metastases and a metastasis diameter of 30 mm. According to univariable logistic regression models the number of inguinal metastases (OR 1.92, p