Comparison of Image Processing Techniques for Nonviable Tissue Quantification in Late Gadolinium Enhancement Cardiac Magnetic Resonance Images

Comparison of Image Processing Techniques for Nonviable Tissue Quantification in Late Gadolinium Enhancement Cardiac Magnetic Resonance Images
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DOI:
10.1097/rti.0000000000000206
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发表时间:
2016-05-01
影响因子:
3.3
通讯作者:
Caiani, Enrico G.
Caiani, Enrico G.
中科院分区:
医学3区
文献类型:
--
作者:
Carminati, M. Chiara;Boniotti, Cinzia;Caiani, Enrico G.

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目的:本研究的目的是比较性能的定量方法,无论是半自动或自动化,左心室(LV)无活力组织分析从心脏磁共振晚期钆增强(CMR-LGE)images.Materials和方法:研究的分割技术是:(i)n-标准偏差阈值,(ii)半高宽阈值,(iii)高斯混合模型分类,(iii)半高宽阈值,(iv)半高宽阈值,(v)半高宽阈值,(iv)模糊c均值聚类。这些算法应用于每个短轴切片(单切片方法)或全局考虑覆盖LV的整个短轴堆栈(全局方法)。从20例缺血性心肌病患者的CMR-LGE图像进行了回顾性选择,并从每种技术的结果进行了评估,对手动tracing.Results:所有方法提供了可比的性能在疤痕检测的准确性,计算局部transmurality,并在疤痕质量的高度相关性与手动技术相比。总体而言,单层和整体方法之间没有显著差异。手动和调查技术的可重复性在所有情况下证实,结果略低的nSD approximates.Conclusions:自动化技术导致准确和可重复的评价左心室疤痕从CMR-LGE缺血性患者的性能类似于手动技术。它们的应用可以最大限度地减少用户交互和计算时间,即使与半自动化方法相比。
Purpose: The aim of this study was to compare the performance of quantitative methods, either semiautomated or automated, for left ventricular (LV) nonviable tissue analysis from cardiac magnetic resonance late gadolinium enhancement (CMR-LGE) images.Materials and Methods: The investigated segmentation techniques were: (i) n-standard deviations thresholding; (ii) full width at half maximum thresholding; (iii) Gaussian mixture model classification; and (iv) fuzzy c-means clustering. These algorithms were applied either in each short axis slice (single-slice approach) or globally considering the entire short-axis stack covering the LV (global approach). CMR-LGE images from 20 patients with ischemic cardiomyopathy were retrospectively selected, and results from each technique were assessed against manual tracing.Results: All methods provided comparable performance in terms of accuracy in scar detection, computation of local transmurality, and high correlation in scar mass compared with the manual technique. In general, no significant difference between single-slice and global approach was noted. The reproducibility of manual and investigated techniques was confirmed in all cases with slightly lower results for the nSD approach.Conclusions: Automated techniques resulted in accurate and reproducible evaluation of LV scars from CMR-LGE in ischemic patients with performance similar to the manual technique. Their application could minimize user interaction and computational time, even when compared with semiautomated approaches.