Measurement of coronary blood flow: a critical review.
Measurement of coronary blood flow: a critical review.
复制标题
冠状动脉血流量的测量：严格审查。
DOI：
10.1016/0022-4804(87)90149-1
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发表时间：
1987
期刊：
影响因子：
--
通讯作者：
Cohn,LH
中科院分区：
文献类型：
--
作者：
Gharagozloo,F;Cohn,LH
在过去的20年里，对正常和病变冠脉循环中冠脉血流生理学的了解已经取得了重大进展。在20世纪60年代和70年代，心脏病学家和心脏外科医生致力于通过药物减少需氧量或通过冠状动脉旁路手术增加供氧量来挽救缺血心肌。今天，部分由于研究冠状动脉循环的日益复杂的技术，治疗性干预现在指向减少甚至逆转由冠状动脉闭塞造成的心肌损害。我们对心肌功能和新陈代谢的更多了解，在一定程度上是由于我们能够测量冠状动脉和心肌血流量。本文将对这些技术进行综述，并尝试区分用于测量冠状动脉血流量的技术和用于测量局部心肌血流的技术。
During the past 20 years significant progress has been made in the understanding of the physiology of coronary blood flow in normal and diseased coronary circulation. In the 1960s and 1970s the cardiologist and the cardiac surgeon focused their efforts on the salvage of ischemic myocardium by reducing oxygen demand pharmacologically or increasing supply by coronary bypass surgery. Today, partly as a result of increasingly sophisticated techniques to study coronary circulation, therapeutic interventions are now directed toward the decrease, or even reversal of, myocardial damage caused by coronary occlusion. Our greater understanding of myocardial function and metabolism has been, in part, due to the ability to measure coronary and myocardial blood flow. This paper will review these techniques and attempt to differentiate between the techniques used for measuring coronary artery blood flow and those for measuring regional myocardial perfusion.