AFFERENT-PROJECTIONS TO THE ORBICULARIS OCULI MOTONEURONAL CELL GROUP - AN AUTORADIOGRAPHICAL TRACING STUDY IN THE CAT
AFFERENT-PROJECTIONS TO THE ORBICULARIS OCULI MOTONEURONAL CELL GROUP - AN AUTORADIOGRAPHICAL TRACING STUDY IN THE CAT
复制标题
DOI：
10.1016/0006-8993(86)90425-7
复制
发表时间：
1986-05-28
期刊：
影响因子：
2.9
通讯作者：
TAN, J
中科院分区：
文献类型：
--
作者：
HOLSTEGE, G;VANHAM, JJ;TAN, J
支配眼轮匝肌的运动神经元在面神经核内形成一个亚群，称为面中间亚核。这使得有可能通过放射自显影追踪技术来研究这些运动神经元的传入。在脑干和间脑进行了多种不同的注射，并研究了向中间面亚核的传入投射。结果表明，这些传入纤维来自下列脑干区：（1）红背核及其背侧的中脑被盖;（2）顶盖前橄榄核和（或）视束核;（3）脑桥被盖背外侧（臂旁核和Kolliker-Ehrman核）和三叉神经主核;（4）三叉神经运动核水平的脑桥被盖腹外侧区：（5）延髓内侧被盖尾侧区;（6）舌下神经核吻极和三叉神经核腹侧部水平的外侧被盖;苍白核和尾中缝大核，包括相邻的延髓被盖。这些后者的预测可能属于一般的运动神经元控制系统。中脑投射以对侧为主，脑桥尾侧和上延髓被盖外侧投射以同侧为主，延髓尾侧投射以双侧为主。提示眼轮匝肌运动神经元的不同传入通路具有不同的功能。脑桥背外侧和延髓被盖外侧的中间神经元可能作为中继皮质和边缘系统的眼轮匝肌肌肉系统的影响，而脑桥腹外侧和延髓被盖尾侧的中间神经元可能参与眨眼反射的神经元组织。
The motoneurons innervating the orbicularis oculi muscle form a subgroup within the facial nucleus, called the intermediate facial subnucleus. This makes it possible to study afferents to these motoneurons by means of autoradiographical tracing techniques. Many different injections were made in the brainstem and diencephalon and the afferent projections to the intermediate facial subnucleus were studied. The results indicated that these afferents were derived from the following brainstem areas: (1) the dorsal red nucleus and the mesencephalic tegmentum dorsal to it; (2) the olivary pretectal nucleus and/or the nucleus of the optic tract; (3) the dorsolateral pontine tegmentum (parabrachial nuclei and nucleus of Kolliker-Fuse) and principal trigeminal nucleus; (4) the ventrolateral pontine tegmentum at the level of the motor trigeminal nucleus; (5) the caudal medullary medial tegmentum; (6) the lateral tegmentum at the level of the rostral pole of the hypoglossal nucleus and the ventral part of the trigeminal nucleus and (7) the nucleus pallidus and caudal raphe magnus including the adjoining medullary tegmentum. These latter projections probably belong to a general motoneuronal control system. The mesencephalic projections are mainly contralateral, the caudal pontine and upper medullary lateral tegmental projections are mainly ipsilateral and the caudal medullary projections are bilateral. It is suggested that the different afferent pathways subserve different functions of the orbicularis oculi motoneurons. Interneurons in the dorsolateral pontine and lateral medullary tegmentum may serve as relay for cortical and limbic influences on the orbicularis oculi musculature, while interneurons in the ventrolateral pontine and caudal medullary tegmentum may take part in the neuronal organization of the blink reflex.