Pain epidemiology and health related quality of life in chronic non-malignant pain patients referred to a Danish multidisciplinary pain center
Pain epidemiology and health related quality of life in chronic non-malignant pain patients referred to a Danish multidisciplinary pain center
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DOI：
10.1016/s0304-3959(97)00126-7
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发表时间：
1997-12-01
期刊：
影响因子：
7.4
通讯作者：
Eriksen, J
中科院分区：
文献类型：
--
作者：
Becker, N;Thomsen, AB;Eriksen, J
本文介绍了丹麦一家多学科疼痛中心连续转诊的150名慢性非恶性疼痛患者的疼痛流行病学和健康相关生活质量(HRQL)的详细研究结果。VAS评分平均疼痛程度为71.6分(SD=18.5)。42%的人报告睡眠质量不佳。采用简明医学结局评定量表(SF-36)、医院焦虑抑郁量表(HAD)和心理一般幸福感量表(PGWB)评定患者的生活质量。与正常人群(NP)相比，SF-36和PGWB得分均显著降低(P<；0.001)，表明躯体、心理和社会幸福感严重降低。在HAD量表中，58%的人被发现患有抑郁症或焦虑症。疼痛严重程度和HRQL之间有统计学意义，但相关性不大。心理幸福感和社会幸福感密切相关。63%的转诊患者有神经源性疼痛状况。在这些患者中，只有25%在转诊时接受了抗抑郁药物或抗惊厥药物的治疗。73%的人在转诊时接受了阿片类药物治疗。阿片类药物用量平均为mg/d(1~280 mg)。与NP相比，慢性疼痛患者在转诊前几年使用医疗保健系统的频率是NP的五倍(P<；0.001)。这项研究证实了慢性疼痛的严重多维影响，并证明了慢性非恶性疼痛患者的HRQL是任何医疗条件下观察到的最低水平之一。(C)1997年国际疼痛研究协会。爱思唯尔科学公司出版。
This paper presents the results of a detailed study of the pain epidemiology and health related quality of life (HRQL) in 150 chronic non-malignant pain patients consecutively referred to a Danish multidisciplinary pain center. Mean pain severity was 71.6 (SD = 18.5) on the VAS scale. Forty-two percent reported poor quality of sleep. HRQL was evaluated with the Medical Outcome Study-Short Form (SF-36), the Hospital Anxiety and Depression scale (HAD) and the Psychological General Well-Being Scale (PGWB). Compared with the normal population (NP) both SF-36 scores and PGWB scores were significantly reduced (P < 0.001) indicating that physical, psychological and social well-being were severely reduced. On the HAD scale 58% were found to have a depressive or anxiety disorder. Statistically significant but modest correlations were found between pain severity and HRQL. Psychological and social well-being was closely correlated. Sixty-three percent of the referred patients had neurogenic pain conditions. Of these, only 25% were treated with antidepressants or anticonvulsants at referral. Seventy-three percent were treated with opioids at referral. Mean opioid consumption was 64 mg of morphine per day (range 1-280 mg). Compared with the NP the chronic pain patients had used the health care system five times more often in the years prior to referral (P < 0.001). The study confirms the severe multidimensional impact of chronic pain and demonstrates that HRQL of chronic non-malignant pain patients is among the lowest observed for any medical condition. (C) 1997 International Association for the Study of Pain. Published by Elsevier Science B.V.