Phase transitions of reversed-phase stationary phases. Cause and effects in the mechanism of retention.
Phase transitions of reversed-phase stationary phases. Cause and effects in the mechanism of retention.
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反相固定相的相变。
DOI：
10.1016/0021-9673(93)80807-k
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发表时间：
1993
期刊：
影响因子：
--
通讯作者：
Dorsey,JG
中科院分区：
文献类型：
--
作者：
Wheeler,JF;Beck,TL;Klatte,SJ;Cole,LA;Dorsey,JG
我们提供了一个有点历史的角度来看，已经完成的工作，支持反相液相色谱键合相的相变的建议。除了这个一般性的审查，我们认为从实践和理论的角度来看，这种转变的影响，在合理的设计改进的反相分离。综述了色谱固定相及相关体系的分析理论和分子模拟方法。初步结果上的温度，密度和链长的依赖性的固定相性能。讨论了计算机模拟在分析过渡行为和保留过程中的作用。
We provide a somewhat historical perspective on the work that has been accomplished that supports the suggestion of phase transitions in reversed-phase liquid chromatographic bonded phases. In addition to this general review, we consider from both a practical and theoretical viewpoint the implications of such transitions in the rational design of improved reversed-phase separations. Analytical theory and molecular simulation approaches to chromatographic stationary phases and related systems are reviewed. Initial results are presented on the temperature, density and chain length dependences of stationary phase properties. The role of computer simulation in analyzing transition behavior and retention processes is discussed.