Methotrexate: Underused and Ignored?
Methotrexate: Underused and Ignored?
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DOI：
10.1159/000342735
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发表时间：
2012-01-01
影响因子：
2.3
通讯作者：
Isaacs, Kim L.
中科院分区：
文献类型：
--
作者：
Herfarth, Hans H.;Long, Millie D.;Isaacs, Kim L.
十多年来，甲氨蝶呤一直被认为是治疗类固醇依赖性活动性克罗恩病的有效治疗剂。然而，国际药物使用数据表明，这种药物很少在临床实践中用于治疗克罗恩病。本综述调查了炎症性肠病患者甲氨蝶呤使用不足的潜在原因。版权所有 (C) 2012 S. Karger AG，巴塞尔
For more than a decade, methotrexate has been known to be an effective therapeutic agent in the treatment of steroid-dependent active Crohn's disease. However, international data on medication utilization suggest that this drug is rarely used in clinical practice for an indication of Crohn's disease. This review investigates the potential reasons for the underuse of methotrexate in patients with inflammatory bowel diseases. Copyright (C) 2012 S. Karger AG, Basel