Lower prevalence of breast cancer and cancers of the reproductive system among former college athletes compared to non-athletes.
Lower prevalence of breast cancer and cancers of the reproductive system among former college athletes compared to non-athletes.
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DOI：
10.1038/bjc.1985.273
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发表时间：
1985-12
影响因子：
8.8
通讯作者：
Marguglio, M
中科院分区：
文献类型：
--
作者：
Frisch, R E;Wyshak, G;Albright, N L;Albright, T E;Schiff, I;Jones, K P;Witschi, J;Shiang, E;Koff, E;Marguglio, M
生殖系统（子宫、卵巢、宫颈和阴道）癌症和乳腺癌的患病率（终生发生率）是根据病史和生殖史、运动训练和饮食数据确定的，共有5 398名在世校友，其中2 622人曾是大学运动员，2 776人是非运动员。前运动员患乳腺癌和生殖系统癌症的风险明显低于非运动员。非运动员/运动员生殖系统癌症的相对危险度（RR）为2.53。95%置信限（CL）（1.17，5.47）。乳腺癌的RR为1.86，95%CL（1.00，3.47）。该分析控制了潜在的混杂因素，包括年龄、癌症家族史、初潮年龄、怀孕次数、口服避孕药的使用、绝经期雌激素的使用、吸烟和消瘦。在大学运动员中，82.4%的人参加过大学预科队，而大学非运动员的比例为24.9%。我们的结论是，长期的运动训练可能会降低乳腺癌和生殖系统癌症的风险。
The prevalence (lifetime occurrence) rate of cancers of the reproductive system (uterus, ovary, cervix and vagina) and breast cancer was determined for 5,398 living alumnae, 2,622 of whom were former college athletes and 2,776 non-athletes, from data on medical and reproductive history, athletic training and diet. The former athletes had a significantly lower risk of cancer of the breast and reproductive system than did the non-athletes. The relative risk (RR), non-athletes/athletes, for cancers of the reproductive system was 2.53. 95% confidence limits (CL) (1.17, 5.47). The RR for breast cancer was 1.86, 95% CL (1.00, 3.47). The analysis controlled for potential confounding factors including age, family history of cancer, age of menarche, number of pregnancies, use of oral contraceptives, use of oestrogen in the menopausal period, smoking, and leanness. Of the college athletes, 82.4% had been on pre-college teams compared to 24.9% of the college non-athletes. We conclude that long term athletic training may lower the risk of breast cancer and cancers of the reproductive system.