The relationship of type A behavior and its components to all-cause mortality in an elderly subgroup of men from the Western Collaborative Group Study

The relationship of type A behavior and its components to all-cause mortality in an elderly subgroup of men from the Western Collaborative Group Study
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DOI:
10.1016/0022-3999(95)00637-0
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发表时间:
1996-05-01
影响因子:
4.7
通讯作者:
Swan, GE
Swan, GE
中科院分区:
医学3区
文献类型:
--
作者:
Carmelli, D;Swan, GE

文献摘要

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这项研究前瞻性地考察了 1,118 名男性(60 至 86 岁)的 A 型行为及其组成部分与全因死亡率的关系,这些男性参与了西方协作组研究的 27 年随访检查。使用改进版的结构化访谈对这些受试者的整体 A/B 行为进行了评估。与此构建相关的其他心理数据是从自我报告问卷中获得的。通过树结构生存分析 (TSSA) 来研究这些数据在控制其他生物风险因素后与 6 年全因死亡率的关系。根据随访时的年龄、A 型行为、Cook-Medley 敌意、吸烟史和癌症状况,TSSA 确定了 6 个在生存率和相关危险因素方面存在差异的亚组。两个亚组的生存率最高,其中一组由年龄较大的 A 型受试者组成,他们在愤怒、敌意和抑郁方面得分最低,另一组则完全由从未吸烟的 B 型受试者组成。在 27 年的随访中,诊断出癌症的受试者的生存率最差,而在年龄、吸烟、A/B 型行为和库克混合敌意方面显着不同的 3 个亚组的生存率中等。本研究首次描述了 A 型老年人的生存率有利和不利的特征。
This study examined prospectively the relationship of Type A behavior and its components to all-cause mortality in 1,118 men (age 60 to 86) who participated in a 27-year follow-up examination of the Western Collaborative Group Study. Global Type A/B behavior was assessed in these subjects using a modified version of the Structured Interview. Additional psychological data that related to this construct were obtained from self-report questionnaires. The relationship of these data, controlling for other biological risk factors, to 6-year all-cause mortality was investigated by means of a tree-structured survival analysis (TSSA). Using age, Type A behavior, Cook-Medley hostility, ever smoking, and cancer status at follow-up, TSSA identified 6 subgroups that differed in survival rates and associated risk factor profiles. The most favorable survival was experienced by 2 subgroups, one composed of older Type A subjects who scored the lowest on anger-hostility and depression, the other consisting entirely of Type B subjects who had never smoked. The worst survival was experienced by subjects with diagnosed cancer at the 27-year follow-up, and intermediate survival rates were experienced by 3 subgroups that differed markedly on age, smoking, Type A/B behavior, and Cook-Medley hostility. The present study is the first to characterize Type A's with favorable and unfavorable survival rates among the elderly.