ACID MUCOPOLYSACCHARIDES AND LIPIDS OF JAPANESE ARTERIES WITH SPECIAL REFERENCE TO ABSENCE OF HYALURONIC ACID IN JAPANESE CEREBRAL ARTERY
ACID MUCOPOLYSACCHARIDES AND LIPIDS OF JAPANESE ARTERIES WITH SPECIAL REFERENCE TO ABSENCE OF HYALURONIC ACID IN JAPANESE CEREBRAL ARTERY
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DOI：
10.1016/s0368-1319(66)80018-2
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发表时间：
1966-01-01
期刊：
影响因子：
--
通讯作者：
YABUTA, N
中科院分区：
文献类型：
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作者：
NAKAMURA, M;ISHIHARA, Y;YABUTA, N
日本动脉树的动脉粥样硬化程度不仅通过基于宏观分级系统的动脉粥样硬化指数来评价，而且还通过酸性粘多糖（AMPS）和脂质的化学分析来评价。除脑动脉总胆固醇外，日本人主动脉、冠状动脉和脑动脉的胆固醇含量及动脉粥样硬化指数均显著低于美国人。脑动脉中氨基己糖、糖醛酸和硫含量明显低于其他动脉。只有脑动脉中的氨基己糖含量随动脉粥样硬化的进展、动脉血压水平的升高和总胆固醇含量的升高而升高，除肾动脉中的氨基己糖含量随收缩压的升高而升高外，其余动脉中的氨基己糖含量均不随动脉粥样硬化的进展、动脉血压水平的升高和总胆固醇含量的升高而升高。脑动脉中透明质酸含量可忽略不计，硫酸软骨素A和/或C含量相对低于主动脉和冠状动脉。
The degree of atherosclerosis of Japanese arterial tree was evaluated not only by atherosclerotic index based on a macroscopial grading system, but also by chemical analyses of acid mucopoly saccharide (AMPS) and lipids. The contents of cholesterol as well as atherosclerotic index of aorta, coronary and cerebral artery of Japanese were significantly lower than those of Americans, except for the total cholesterol of cerebral artery. The contents of hexosamine, uronic acid and sulfur in cerebral artery are significantly lower than those in other arteries. Only in cerebral arteries, the contents of hexosamine increased with an advancement of atherosclerosis, an increase of arterial blood pressure levels and of the contents of total cholesterol, but not in other arteries except that hexosamine contents of renal artery increased with an increase of systolic blood pressure. In cerebral artery, the content of hyaluronic acid is negligible and that of chondroitin sulfate A and/or C is relatively lower than that in aorta and coronary artery.