Statistical limitations in ion imaging.
Statistical limitations in ion imaging.
复制标题
离子成像中的统计限制。
DOI：
10.1088/1361-6560/abee57
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发表时间：
2021-05-10
影响因子：
3.5
通讯作者：
Evans PM
中科院分区：
文献类型：
--
作者：
Collins-Fekete CA;Dikaios N;Bär E;Evans PM
在这项研究中，我们研究了各种离子束用于放射治疗的能力，以产生高质量的相对停止功率图，从能量损失测量中获得。比较不同离子的图像质量指标是作为剂量和空间分辨率函数的信噪比（SNR）。Geant4蒙特卡罗模拟了氢、氦、锂、硼和碳离子束穿过直径20 cm的水影，以确定信噪比和空间分辨率。在一定范围内，由于质子核稳定性和每次初级剂量低，质子的信噪比明显高于其他离子（比氦高36%）。然而，对于具有相同初始范围的光束，它也产生了对所有其他离子的最低空间分辨率，与碳成像相比，分辨率降低了4倍。当比较固定空间分辨率为10 lp cm−1时，碳离子产生最高的图像质量指标，质子离子产生最低的图像质量指标。总之，我们发现没有离子可以同时最大化所有图像质量指标，必须在空间分辨率、信噪比和剂量之间做出选择。
In this study, we investigated the capacity of various ion beams available for radiotherapy to produce high quality relative stopping power map acquired from energy-loss measurements. The image quality metrics chosen to compare the different ions were signal-to-noise ratio (SNR) as a function of dose and spatial resolution. Geant4 Monte Carlo simulations were performed for: hydrogen, helium, lithium, boron and carbon ion beams crossing a 20 cm diameter water phantom to determine SNR and spatial resolution. It has been found that protons possess a significantly larger SNR when compared with other ions at a fixed range (up to 36% higher than helium) due to the proton nuclear stability and low dose per primary. However, it also yields the lowest spatial resolution against all other ions, with a resolution lowered by a factor 4 compared to that of carbon imaging, for a beam with the same initial range. When comparing for a fixed spatial resolution of 10 lp cm−1, carbon ions produce the highest image quality metrics with proton ions producing the lowest. In conclusion, it has been found that no ion can maximize all image quality metrics simultaneously and that a choice must be made between spatial resolution, SNR, and dose.
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影响因子：
3.5
作者：
Collins-Fekete, Charles-Antoine;Bar, Esther;Seco, Joao
通讯作者：
Seco, Joao
影响因子：
3.5
作者：
Collins-Fekete, Charles-Antoine;Volz, Lennart;Seco, Joao
通讯作者：
Seco, Joao
影响因子：
3.5
作者：
Arbor, N.;Dauvergne, D.;Rit, S.
通讯作者：
Rit, S.
影响因子：
--
作者：
Goudsmit, S;Saunderson, JL
通讯作者：
Saunderson, JL
影响因子：
3.5
作者：
Raedler, Martin;Landry, Guillaume;Dedes, George
通讯作者：
Dedes, George