Conjugated-Polymer-Based Energy-Transfer Systems for Antimicrobial and Anticancer Applications
Conjugated-Polymer-Based Energy-Transfer Systems for Antimicrobial and Anticancer Applications
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用于抗菌和抗癌应用的基于共轭聚合物的能量传输系统
DOI：
10.1002/adma.201400379
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发表时间：
2014-10-29
影响因子：
29.4
通讯作者：
Wang, Shu
中科院分区：
文献类型：
--
作者：
Yuan, Huanxiang;Wang, Bing;Wang, Shu
共轭聚合物（CP）在传感，成像和生物医学应用中吸引了很多关注，因为最近的成就在这篇研究新闻文章中突出显示。本文综述了近年来CP类能量传递系统在抗微生物和抗癌治疗中的应用进展。激发能从CP转移到光敏剂导致产生活性氧（ROS），其能够有效地杀死周围环境中的病原微生物和癌细胞。荧光共振能量转移（FRET）和生物发光能量转移（BRET）模式进行了讨论。
Conjugated polymers (CPs) attract a lot of attention in sensing, imaging, and biomedical applications because of recent achievements that are highlighted in this Research News article. A brief review of recent progress in the application of CP-based energy-transfer systems in antimicrobial and anticancer treatments is provided. The transfer of excitation energy from CPs to photosensitizers leads to the generation of reactive oxygen species (ROS) that are able to efficiently kill pathogenic microorganisms and cancer cells in the surroundings. Both fluorescence resonance energy transfer (FRET) and bioluminescence energy transfer (BRET) modes are discussed.