Focus on breast cancer

Focus on breast cancer
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DOI:
10.1016/s1535-6108(02)00066-1
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发表时间:
2002-05-01
期刊:
影响因子:
50.3
通讯作者:
Norton, L
Norton, L
中科院分区:
医学1区
文献类型:
--
作者:
Baselga, J;Norton, L

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乳腺癌是西方国家女性中最常见的恶性肿瘤,在美国的发病率为每100,000女性年(wy)111例,死亡率为每100,000 wy 24例死亡(Howe et al.,2001年)。据估计,世界上每年有100万例新病例,东亚的发病率比西方国家低5倍,这种变化可能与环境因素而不是遗传因素有关(Probst-Hensch等人,2000年)。乳腺癌的危险因素包括:
Breast cancer is the most frequent malignancy among women in Western countries, with an incidence rate in the US of 111 cases per 100,000 woman-years (wy) and a mortality rate of 24 deaths per 100,000 wy (Howe et al., 2001). There are an estimated 1 million new cases per year in the world, with up to 5-fold lower incidence in Eastern Asia than in Western countries, a variation probably related to environmental rather than genetic factors (Probst-Hensch et al., 2000). Established risk factors for breast cancer include: