easyLINKAGE: a PERL script for easy and automated two-/multi-point linkage analyses
easyLINKAGE: a PERL script for easy and automated two-/multi-point linkage analyses
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DOI：
10.1093/bioinformatics/bti009
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发表时间：
2005-02-01
期刊：
影响因子：
5.8
通讯作者：
Hoffmann, K
中科院分区：
文献类型：
--
作者：
Lindner, TH;Hoffmann, K
我们已经生成了程序easyLINKAGE，它结合了自动化设置和性能的联动分析和模拟下，易于处理的图形用户界面为Microsoft Windows 2000/XP和标准的UNIX系统。该程序包支持两点连锁分析（FastLink v4.1和SPLink v1.09）、多点连锁分析[GENEHUNTER v2.1、经Kong和考克斯v1.2（等位基因共享建模）校正的GENEHUNTER-PLUS]和模拟包SLINK v2.65，并提供LOD评分、NPL评分、P值和其他参数的全基因组和染色体postscript图。
We have generated the program easyLINKAGE that combines automated setup and performance of linkage analyses and simulation under an easy to handle graphical user interface for Microsoft Windows 2000/XP and standard UNIX systems. The program package supports two-point linkage analyses (FastLink v4.1 and SPLink v1.09), multi-point linkage analyses [GENEHUNTER v2.1, GENEHUNTER-PLUS with the emendation by Kong and Cox v1.2 (allele sharing modelling)] and the simulation package SLINK v2.65, and provides genome-wide as well as chromosomal postscript plots of LOD scores, NPL scores, P-values and other parameters.