A pilot study of the continuous glucose monitoring system - Clinical decisions and glycemic control after its use in pediatric type 1 diabetic subjects

A pilot study of the continuous glucose monitoring system - Clinical decisions and glycemic control after its use in pediatric type 1 diabetic subjects
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DOI:
10.2337/diacare.24.12.2030
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发表时间:
2001-12-01
期刊:
影响因子:
16.2
通讯作者:
Pitukcheewanont, P
Pitukcheewanont, P
中科院分区:
医学1区
文献类型:
--
作者:
Kaufman, FR;Gibson, LC;Pitukcheewanont, P

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目的:确定连续血糖监测系统(CGMS) (MiniMed, Sylmar, CA)是否可以用于临床决策,以及它是否对儿童I型糖尿病受试者的血糖有影响。研究设计和方法:招募有HbA(1c)≥8.0%且有管理问题的儿科受试者(n = 35),或HbA(1c)≥8.0%的严重或夜间低血糖发作或低血糖不意识发作(n = 12)。共有47例患者,平均HbA(1c)值为8.6 +/- 1.6%(平均年龄11.8 +/- 4.6岁,最年轻2.7岁,糖尿病病程5.5 +/- 3.5年)接受3 - 4次胰岛素注射/天(n = 24)或胰岛素泵治疗(n = 23), CGMS随访平均69.5 +/- 28小时。比较高(>150 mg/dl)和低(
OBJECTIVE - To determine whether the continuous glucose monitoring system (CGMS) (MiniMed, Sylmar, CA) could be used to make clinical decisions and whether it has an impact on glycemia in pediatric type I diabetic subjects.RESEARCH DESIGN AND METHODS - Pediatric subjects were recruited if they had HbA(1c) >8.0% with management problems (n = 35) or episodes of severe or nocturnal hypoglycemia or hypoglycemia unawareness associated with HbA(1c) less than or equal to8.0% (n = 12). A total of 47 patients with a mean HbA(1c) value of 8.6 +/- 1.6% (mean age 11.8 +/- 4.6 years, youngest 2.7 years, and diabetes duration 5.5 +/- 3.5 years) on three to four insulin injections/day (n = 24) or insulin pump therapy (n = 23) were followed with the CGMS for a mean of 69.5 +/- 28 h. Comparisons were made between the number of high (>150 mg/dl) and low (