Evidence for increased susceptibility of Brugia pahangi-infected jirds (Meriones unguiculatus) to subsequent homologous infections
Evidence for increased susceptibility of Brugia pahangi-infected jirds (Meriones unguiculatus) to subsequent homologous infections
复制标题
有证据表明，受彭亨布鲁氏菌感染的沙鼠（Meriones unguiculatus）对随后的同源感染的易感性增加
DOI：
10.1017/s0022149x00006532
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发表时间：
1980
影响因子：
1.6
通讯作者：
John B. Malone
中科院分区：
文献类型：
--
作者：
Thomas R. Klei;John W. McCall;John B. Malone
摘要利用攻毒前感染4个月和8个月的沙鼠研究了现有的巴汉丝虫感染对建立后续种群的影响。攻毒接种后28天进行尸检，以分离攻毒和初始蠕虫种群。结果表明，持续时间为4或8个月的现有感染增加了对后续同源感染的易感性。在先前感染和未感染的组之间，检查的组织部位中挑战种群蠕虫的位置没有显著差异。先前的感染并不影响挑战种群蠕虫的早期生长，如其长度所示。
ABSTRACT The effect of existing Brugia pahangi infections on the establishment of a subsequent population was studied using jirds which had pre-challenge infections of 4 and 8 months duration. Necropsies were performed 28 days post-challenge inoculation in order to separate challenge and initial worm populations. The results indicate that existing infections of 4 or 8 months duration increase the susceptibility to subsequent homologous infections. The location of challenge population worms in tissue sites examined did not differ significantly between previously infected and uninfected groups. Previous infections did not affect the early growth of challenge population worms as indicated by their length.