Malignant solitary fibrous tumor of the right atrium.
Malignant solitary fibrous tumor of the right atrium.
复制标题
右心房恶性孤立性纤维瘤。
DOI：
10.1097/maj.0b013e318259b317
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发表时间：
2012
影响因子：
3.1
通讯作者：
G. Jiang
中科院分区：
文献类型：
--
作者：
Xiao;Hao Wang;Yan;Gang Chen;G. Jiang
心脏孤立性纤维瘤（SFTs）是非常罕见的，迄今为止只有4例。在这里，我们描述的情况下，一个55岁的男子与原发性，恶性SFT出现在他的心脏的右心房。他的主诉是胸闷和呼吸急促。体格检查显示颈静脉充血。计算机断层扫描显示前纵隔有一个15 × 10 × 8 cm的肿瘤。在体外循环下手术切除肿瘤。在右心房内发现一个灰白色白色肿瘤。肿瘤的组织学表现为梭形细胞的高细胞化分布，核内有核小体，排列成故事状，并与胶原间质混合。免疫组化显示肿瘤为CD34阳性。根据上述特征，诊断为恶性SFT。患者随后因呼吸和循环衰竭死亡。
Cardiac solitary fibrous tumors (SFTs) are extremely rare, with only 4 cases described to date. Here, we describe the case of a 55-year-old man with a primary, malignant SFT that arose in the right atrium of his heart. His presenting complaint was of chest distress and shortness of breath. Physical examination revealed jugular venous engorgement. Computed tomography showed a tumor of 15 × 10 × 8 cm in the anterior mediastinum. The tumor was surgically resected under cardiopulmonary bypass. A grayish white neoplasm was discovered lying within the right atrium. The histological appearance of the tumor was of a hypercellular distribution of spindle cells with nuclear atypia, arranged in a storiform pattern and intermixed with collagenous stroma. Immunohistochemistry showed that the tumor was positive for CD34. Based on the aforementioned features, the diagnosis of malignant SFT was made. The patient subsequently died as a result of respiratory and circulatory failure.