Bilineage acute leukemia of T-lymphoid and myeloid lineages.
Bilineage acute leukemia of T-lymphoid and myeloid lineages.
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DOI：
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发表时间：
2004
期刊：
影响因子：
10.1
通讯作者：
N. Kobayashi;K. Matsuda;K. Sakashita;S. Matsuzaki;Ryu Iwasaki;K. Koike
中科院分区：
文献类型：
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作者：
N. Kobayashi;K. Matsuda;K. Sakashita;S. Matsuzaki;Ryu Iwasaki;K. Koike
我们报告一例以T细胞白血病和粒单核细胞白血病共存为特征的费城染色体阴性双系白血病的病例。对遗传标记和增殖/分化潜能的比较分析表明，具有分化为髓系潜能的T系干细胞有可能恶性转化。
We report the case of a child with Philadelphia chromosome-negative bilineage leukemia characterized by the coexistence of T-cell leukemia and myelomonocytic leukemia. Comparative analyses of genetic markers and proliferative/differentiative potential show the possibility of malignant transformation of a T-lineage stem cell with the potential to differentiate into the myeloid lineage.