Gastrointestinal Diseases in Pregnancy Nausea, Vomiting, Hyperemesis Gravidarum, Gastroesophageal Reflux Disease, Constipation, and Diarrhea
Gastrointestinal Diseases in Pregnancy Nausea, Vomiting, Hyperemesis Gravidarum, Gastroesophageal Reflux Disease, Constipation, and Diarrhea
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DOI：
10.1016/j.gtc.2016.02.005
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发表时间：
2016-06-01
影响因子：
3.7
通讯作者：
Christie, Jennifer A.
中科院分区：
文献类型：
--
作者：
Body, Cameron;Christie, Jennifer A.
许多胃肠道疾病在怀孕期间很常见。孕酮水平升高可能导致胃肠动力改变，这可能导致恶心、呕吐和/或GERD。妊娠引起的腹泻可能是由于高水平的甘草素。本文综述了与妊娠相关的正常生理和结构变化，这些变化可能导致妊娠患者的许多常见胃肠道疾病。此外，适当的临床和实验室评估，其他病理条件，应包括在差异，以及非药物和药物治疗这些条件进行了讨论。
Many disorders of the gastrointestinal tract are common in pregnancy. Elevated levels of progesterone may lead to alterations in gastrointestinal motility which could contribute to nausea, vomiting, and/or GERD. Pregnancy-induced diarrhea may be due to elevated levels prostaglandins. This article reviews the normal physiologic and structural changes associated with pregnancy that could contribute to many of the common gastrointestinal complaints in pregnant patients. Additionally, the appropriate clinical and laboratory evaluations, other pathologic conditions that should be included in the differential, as well as the nonpharmacologic and pharmacologic therapies for each of these conditions is discussed.