Three new vibralactone-related compounds from cultures of Basidiomycete Boreostereum vibrans
Three new vibralactone-related compounds from cultures of Basidiomycete Boreostereum vibrans
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DOI：
10.1080/10286020.2014.901312
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发表时间：
2014-05
影响因子：
1.7
通讯作者：
Gang-qiang Wang;Kun Wei;Ling Zhang;Zheng-Hui Li;Qiu-an Wang;Jikai Liu
中科院分区：
文献类型：
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作者：
Gang-qiang Wang;Kun Wei;Ling Zhang;Zheng-Hui Li;Qiu-an Wang;Jikai Liu
本文报道了从担子菌Boreostereum vibrans的培养物中分离得到的三个新化合物，命名为vibralactones K-M（1-3）和vibralactone（4）。通过波谱学（1D和2D NMR、HRMS、UV和IR）、化学方法和文献数据确定了它们的结构。没有一种化合物对五种人类癌细胞系具有细胞毒性，并且对胰脂肪酶具有抑制活性。
Three new compounds, named as vibralactones K–M (1–3), together with vibralactone (4) have been isolated from cultures of the Basidiomycete Boreostereum vibrans. Their structures were determined on the basis of spectroscopic evidences (1D and 2D NMR, HRMS, UV, and IR data), chemical methods and literature data. None of the compounds was cytotoxic against five human cancer cell lines and showed inhibitory activity on the pancreatic lipase.