Highly ortho-selective cross-coupling of dichlorobenzene derivatives with Grignard reagents.
Highly ortho-selective cross-coupling of dichlorobenzene derivatives with Grignard reagents.
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DOI：
10.1021/ol702646s
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发表时间：
2007-11
期刊：
影响因子：
5.2
通讯作者：
S. Ishikawa;K. Manabe
中科院分区：
文献类型：
--
作者：
S. Ishikawa;K. Manabe
利用Pd2（dba）3和PCy3的组合实现了二氯苯衍生物与格氏试剂的高邻位选择性交叉偶联。羟基化三苯膦的使用进一步改善了二氯苯酚和二氯苯胺的反应。
Highly ortho-selective cross-coupling of dichlorobenzene derivatives with Grignard reagents was realized using a combination of Pd2(dba)3 and PCy3. Use of hydroxylated terphenylphosphines further improved the reactions of dichlorophenol and dichloroaniline.