Hypertension in pregnancy: is it time for a new approach to treatment?
Hypertension in pregnancy: is it time for a new approach to treatment?
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DOI：
10.1097/hjh.0b013e3283536319
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发表时间：
2012-06
影响因子：
4.9
通讯作者：
Garovic VD
中科院分区：
文献类型：
--
作者：
Moser M;Brown CM;Rose CH;Garovic VD
高血压疾病是全世界与妊娠有关的孕产妇死亡的主要原因。与普通人群中高血压治疗的建议不同，美国目前对妊娠期间血压升高的定义和治疗建议多年来一直保持不变。临床研究提供了令人信服的证据表明，患有妊娠期高血压疾病的女性有发生心血管并发症的即时和长期风险;这些研究结果表明，应考虑降低目前推荐的血压阈值，无论是用于治疗的开始还是治疗目标，并简化妊娠期血压升高的管理方法。本文综述了目前妊娠期高血压疾病的治疗策略，高血压领域的新进展，一般情况下，特别是在妊娠患者中，以及它们对当代血压目标的潜在影响和妊娠期特定降压药物的使用。
Hypertensive disorders represent major causes of pregnancy-related maternal mortality worldwide. The current definition and treatment recommendations for elevated blood pressure during pregnancy in the US have remained unchanged for many years, unlike the recommendations for hypertension treatment in the general population. Clinical studies have provided convincing evidence that women with hypertensive pregnancy disorders are at both immediate and long-term risk for cardiovascular complications; these findings suggest that consideration be given to lowering the presently recommended blood pressure thresholds, both for the initiation of therapy and for therapeutic targets, and to simplifying the approach to the management of elevated blood pressure in pregnancy. This review focuses on the current treatment strategies for hypertensive pregnancy disorders, new developments in the field of hypertension, in general, and in pregnant patients, in particular, and their potential impact on contemporary blood pressure goals and the use of specific antihypertensive medications in pregnancy.