Using Timed Up-and-Go to Identify Frail Members of the Older Population
Using Timed Up-and-Go to Identify Frail Members of the Older Population
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DOI：
10.1093/gerona/gls190
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发表时间：
2013-04-01
影响因子：
5.1
通讯作者：
Kenny, Rose Anne
中科院分区：
文献类型：
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作者：
Savva, George M.;Donoghue, Orna A.;Kenny, Rose Anne
Fried对脆弱性的定义被广泛使用，但它的测量是有问题的。Timed Up-and-Go(TUG)是一种简单的移动性衡量标准，可以作为脆弱性的有用指标。在这里，我们描述了脆弱和TUG在爱尔兰老年人口中的分布，并讨论了TUG在多大程度上识别脆弱和早衰人口。爱尔兰65岁及以上人口老龄化纵向研究的1814名参与者完成了一项全面的健康评估。虚弱的定义是，有三个或三个以上的步态速度低，握力低，无意中体重减轻，自我报告筋疲力尽，以及缺乏体力活动。ROC曲线被用来识别TUG对虚弱和早衰人群的区分程度，以及TUG是否将步速提高作为衡量虚弱的单一客观指标。在65岁及以上的爱尔兰人口中，7.7%的人是虚弱的，44.0%的人是早衰的。TUG能很好地识别人群中的脆弱成员(AUC 0.87)，但较不能区分弱势或弱势群体(AUC 0.73)。TUG捕捉到了随着年龄增长而变得更加常见的脆弱成分，但并不区分不会导致意外体重减轻或疲惫的成分。在识别脆弱方面，使用TUG代替步态速度没有优势。TUG是一种敏感和特异的脆弱测量方法，在完全应用或解释Fried标准不可行的情况下，TUG具有优势；然而，TUG不能可靠地识别脆弱前期个体。
Frieds definition of frailty is widely used but its measurement is problematic. Timed up-and-go (TUG) is a simple measure of mobility that may be a useful proxy for frailty. Here, we describe the distribution of frailty and TUG in the older population of Ireland and discuss the extent to which TUG identifies the frail and prefrail populations.A total of 1,814 participants of The Irish Longitudinal Study on Ageing aged 65 and older completed a comprehensive health assessment. Frailty was defined by having three or more of low gait speed, low grip strength, unintentional weight loss, self-reported exhaustion, and low physical activity. ROC curves were used to identify how well TUG discriminates the frail and prefrail populations and whether TUG improves on gait speed as a single objective measure of frailty.Among the Irish population aged 65 and older, 7.7% were frail and 44.0% were prefrail. TUG identifies frail members of the population well (AUC 0.87) but is less able to discriminate the nonfrail from the prefrail or frail populations (AUC 0.73). TUG captures the components of frailty that become more common with age but does not discriminate the components that do not, for example, unintended weight loss or exhaustion. There is no advantage in using TUG instead of gait speed with respect to identifying frailty.TUG is a sensitive and specific measure of frailty that offers advantages in its measurement where the full application or interpretation of Frieds criteria is impracticable; however, TUG cannot be used to reliably identify prefrail individuals.