Potential benefits and limitations of utilizing chondroprogenitors in cell-based cartilage therapy.

Potential benefits and limitations of utilizing chondroprogenitors in cell-based cartilage therapy.
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DOI:
10.3109/03008207.2015.1040547
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发表时间:
2015
影响因子:
2.9
通讯作者:
Chen Q
Chen Q
中科院分区:
医学3区
文献类型:
--
作者:
Jayasuriya CT;Chen Q

文献摘要

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Chondroprogenitor cells are a subpopulation of multipotent progenitors that are primed for chondrogenesis. They are believed to have the biological repertoire to be ideal for cell-based cartilage therapy. In addition to summarizing recent advances in chondroprogenitor cell characterization, this review discusses the projected pros and cons of utilizing chondroprogenitors in regenerative medicine and compares them to that of preexisting methods, including autologous chondrocyte implantation (ACI) and the utilization of bone marrow derived mesenchymal stem cells (MSCs) for the purpose of cartilage tissue repair.