Depressive symptoms, menopausal status, and climacteric symptoms in women at midlife
Depressive symptoms, menopausal status, and climacteric symptoms in women at midlife
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DOI：
10.1097/00006842-200107000-00013
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发表时间：
2001-07-01
影响因子：
3.3
通讯作者：
Siegler, IC
中科院分区：
文献类型：
--
作者：
Bosworth, HB;Bastian, LA;Siegler, IC
目的：先前的研究发现，45岁至54岁的女性抑郁症发病率增加，但影响这些发病率的因素尚不清楚。评估抑郁症状的高发率是否与绝经状态、更年期症状和激素替代疗法的使用有关。设计：横断面调查。设置：社区样本。方法：1998年10月至1999年2月对581名年龄在45 ~ 54岁之间的女性进行了电话访谈。测量方法：用缩写CES-D（一种抑郁症状筛查方法）测量抑郁症。根据妇女报告的绝经期感知、前12个月的月经频率和卵巢切除术史，将她们的绝经状态分为四类：(1)无绝经迹象；(2)接近更年期；(3)已进入更年期；(4)已完成更年期。结果：168名妇女（28.9%）在使用简略的CES-D量表时出现高水平（大于或等于10）抑郁症状。在logistic回归分析中，与抑郁症状增加相关的重要因素包括缺乏运动、收入不足、使用雌激素/孕激素组合以及存在更年期症状（睡眠困难、情绪波动或记忆问题）。绝经状态与抑郁症状无关。结论：在45至54岁的女性样本中，更年期症状而非绝经状态与抑郁症状的高发率相关。
Objective: Previous studies have found increased rates of depression in women aged 45 to 54 years, but the factors that influence these rates are not understood. It was assessed whether higher rates of depressive symptoms were associated with menopausal status, climacteric symptoms, and use of hormone replacement therapy. Design: Cross-sectional survey. Setting: Community sample. Methods: Data are from 581 women ages 45 to 54 years who were interviewed by telephone between October 1998 and February 1999. Measures: Depression was measured with the abbreviated CES-D, a depressive symptoms screening measure. Women's reported perception of menopausal stage, frequency of periods in the preceding 12 months, and history of oophorectomy were used to classify their menopausal status into four categories: (1) no indication of menopause; (2) close to menopause; (3) had begun menopause; and (4) had completed menopause. Results: There were 168 women (28.9%) who reported a high level (greater than or equal to 10) of depressive symptoms when the abbreviated CES-D was used. In a logistic-regression analysis, significant factors associated with increased depressive symptoms included physical inactivity, inadequate income, use of estrogen/progesterone combination, and presence of climacteric symptoms (trouble sleeping, mood swings, or memory problems). Menopausal status was not associated with depressive symptoms. Conclusions: In this sample of women age 45 to 54 years, climacteric symptoms but not menopausal status were associated with higher rates of depressive symptoms.