Resistance of Aedes aegypti from the state of São Paulo, Brazil, to organophosphates insecticides
Resistance of Aedes aegypti from the state of São Paulo, Brazil, to organophosphates insecticides
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DOI：
10.1590/s0074-02762003000500020
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发表时间：
2003-07-01
期刊：
影响因子：
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通讯作者：
Bracco, José Eduardo
中科院分区：
文献类型：
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作者：
Macoris, Maria de Lourdes G;Andrighetti, Maria Teresa M;Bracco, José Eduardo
自从 1980 年代中期埃及伊蚊重新引入圣保罗州以来，有机磷杀虫剂就被用来控制登革热媒介。 1996 年，制定了年度监测白伊菌敏感性的计划。对埃及伊蚊实施了杀虫剂。介绍了该监测计划的一些结果。艾。已对十个地区的埃及伊蚊种群进行了诊断剂量的替美磷和杀螟松的生物测定。只有两种（玛丽莉亚和总统普鲁登特）仍然对这两种杀虫剂敏感，一种（桑托斯）表现出真正的抗药性。艾。其余地区的埃及伊蚊表现出初步的易感性改变。对替美磷的耐药率从 1.2 到 2.9 不等，对杀螟硫磷的耐药率从 1.5 到 3.2 不等，表明具有中等程度的耐药性。生化测定没有检测到乙酰胆碱酯酶的变化，但表明抗性与酯酶有关。
Since the reintroduction of Aedes aegypti in the state of Sao Paulo, in the middle of the 1980-decade, organophosphate insecticides are being used to control the dengue vector. In 1996, an annual program for monitoring the susceptibility of Ae. aegypti to the insecticides was implemented. Some of the results of this monitoring program are presented. Ae. aegypti populations from ten localities have been submitted to bioassays with the diagnostic dose of temephos and fenitrothion. Only two (Marilia and Presidente Prudente) remain susceptible to both insecticides and one (Santos) exhibits true resistance. Ae. aegypti from the remaining localities showed an incipient altered susceptibility. Resistance ratios varied from 1.2 to 2.9 for temephos and from 1.5 to 3.2 to fenitrothion, indicating moderate levels of resistance. Biochemical assays did not detect alterations in the enzyme acetilcholinesterase, but indicated that resistance is associated with esterases.