Material removal mechanism in and experiments of electrorheological polishing of foldable intraocular lenses at low temperatures
Material removal mechanism in and experiments of electrorheological polishing of foldable intraocular lenses at low temperatures
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DOI：
10.1016/j.jmapro.2023.06.047
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发表时间：
2023-09
影响因子：
6.2
通讯作者：
Cheng Fan;Xingfeng Wang;Kaixuan Liu;Yigang Chen;Fusheng Liang;Zhaoxiang Wang;Jun Zhao
中科院分区：
文献类型：
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作者：
Cheng Fan;Xingfeng Wang;Kaixuan Liu;Yigang Chen;Fusheng Liang;Zhaoxiang Wang;Jun Zhao
制造可折叠丙烯酸酯人工晶状体（IOL）的传统方法包括注射成型和超精密金刚石车削。由于缺乏对柔软柔性生物材料材料去除机理的深入研究，传统的加工方法无法生产出高质量的可折叠IOL表面。本文提出了一种新的低温辅助电流变抛光的制造方法，以提高折叠式人工晶状体的表面质量。温度对力学性能的影响，包括分子链末端的平均方位角位移、扩散系数、应力-应变响应等，采用分子动力学方法系统地研究了电流变效应下磨粒材料去除机理随温度的演化规律。随着温度的降低，通过磨料颗粒从IOL表面去除材料的机制从压实去除变为沟槽去除，表面粗糙度降低，这表明丙烯酸酯材料的可加工性在低温（约-20 °C）下可以大大改善。此外，设计了一种新型的低温辅助电流变抛光系统。正交试验表明，温度对表面粗糙度的影响最显著，与分子动力学分析结果一致。在-20 °C下抛光的材料表面粗糙度从491 nm降低到9 nm，表明低温辅助电流变抛光是一种高效、高质量制备可折叠丙烯酸酯IOL的有效方法。
The traditional method of manufacturing foldable acrylate intraocular lenses (IOLs) involves injection molding and ultraprecision diamond turning. Due to the lack of in-depth research on the material removal mechanism for soft and flexible biomaterials, traditional processing methods cannot produce high-quality surfaces of foldable IOLs. This paper presents a new manufacturing method of low-temperature-assisted electrorheological polishing to improve the surface quality of foldable IOLs. The effects of temperature on the mechanical properties, including the mean azimuth shift at the end of the molecular chain, diffusion coefficient, stress-strain response, etc., and the evolution of the material removal mechanism of abrasive particles under the electrorheological effect with temperature were systematically studied by molecular dynamics. With decreasing temperature, the mechanism of material removal from the IOL surface by abrasive particles changed from compaction removal to furrow removal, and the surface roughness decreased, which revealed that the machinability of the acrylate material could be greatly improved at low temperatures (approximately −20 °C). In addition, a new low-temperature-assisted electrorheological polishing system for IOLs was designed. An orthogonal test showed that the temperature had the most significant influence on the surface roughness, consistent with the molecular dynamics analysis results. The surface roughness of the material polished at −20 °C decreased from 491 nm to 9 nm, which indicates that low-temperature-assisted electrorheological polishing is an effective method for fabricating foldableacrylate IOLs with high efficiency and quality.