Study protocol: the empirical investigation of methods to correct for measurement error in biobanks with dietary assessment
Study protocol: the empirical investigation of methods to correct for measurement error in biobanks with dietary assessment
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DOI：
10.1186/1471-2288-11-135
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发表时间：
2011-10-05
影响因子：
4
通讯作者：
Minelli, Cosetta
中科院分区：
文献类型：
--
作者：
Bennett, Derrick A.;Little, Julian;Minelli, Cosetta
背景资料：基因组学公共人口项目（P（3）G）是一个旨在促进基于人口的基因组学领域研究人员之间合作的组织。P（3）G的主要目标是鼓励研究人员和生物库之间的合作，优化研究设计，促进生物库中信息使用的协调，并促进相关方之间的知识转移。环境暴露评估方法的校准和协调的重要性，以允许在基因-环境相互作用的评估中汇集研究数据，已得到P（3）G的认可，该组织已成立了一个校准方法学小组，目的是：1）审查已发表的关于测量误差校正方法的方法学文献，包括假设和实施方法;（2）审查已发表的使用校准方法的营养流行病学研究中的可用证据;（3）以比较图表的形式传播关于进行校准研究的方法以及如何获得校正因子的信息，以支持在P（3）G网络内合作的不熟悉所采用方法的研究小组; 4）应用于营养流行病学领域，包括基因-饮食相互作用，最终发展出一个各种营养素典型校正因子的清单。方法/设计：系统回顾（a）流行病学研究中校正测量误差方法的方法学文献;和（B）主要设计用于调查饮食与疾病之间的关联并校正饮食摄入量测量误差的研究。讨论：对关于校准的方法学文献进行系统性审查将有助于评价校正测量误差的方法，并有助于设计生物库前瞻性合并的校准研究。这可以提高此类研究设计的效率，提高统计能力，减少偏倚，并有助于评估复杂疾病中基因-环境相互作用的影响。对膳食摄入信息校准的系统性审查可以为基因-膳食相互作用研究提供信息，这些研究涉及汇集以不同方式收集的营养数据的研究结果。
Background: The Public Population Project in Genomics (P(3)G) is an organisation that aims to promote collaboration between researchers in the field of population-based genomics. The main objectives of P(3)G are to encourage collaboration between researchers and biobankers, optimize study design, promote the harmonization of information use in biobanks, and facilitate transfer of knowledge between interested parties. The importance of calibration and harmonisation of methods for environmental exposure assessment to allow pooling of data across studies in the evaluation of gene-environment interactions has been recognised by P(3)G, which has set up a methodological group on calibration with the aim of; 1) reviewing the published methodological literature on measurement error correction methods with assumptions and methods of implementation; 2) reviewing the evidence available from published nutritional epidemiological studies that have used a calibration approach; 3) disseminating information in the form of a comparison chart on approaches to perform calibration studies and how to obtain correction factors in order to support research groups collaborating within the P(3)G network that are unfamiliar with the methods employed; 4) with application to the field of nutritional epidemiology, including gene-diet interactions, ultimately developing a inventory of the typical correction factors for various nutrients.Methods/Design: Systematic review of (a) the methodological literature on methods to correct for measurement error in epidemiological studies; and (b) studies that have been designed primarily to investigate the association between diet and disease and have also corrected for measurement error in dietary intake.Discussion: The conduct of a systematic review of the methodological literature on calibration will facilitate the evaluation of methods to correct for measurement error and the design of calibration studies for the prospective pooling of biobanks. This could increase the efficiency of the design of such studies, improve statistical power, reduce bias, and aid in the assessment of gene-environment interaction effects in complex diseases. The systematic review of calibration of dietary intake information could inform gene-diet interaction investigations involving the pooling of results from studies with nutritional data collected in different ways.