Immunology of AIDS related to psoriasis.
Immunology of AIDS related to psoriasis.
复制标题
与牛皮癣相关的艾滋病免疫学。
DOI：
10.1111/1523-1747.ep12505743
复制
发表时间：
1990
期刊：
影响因子：
--
通讯作者：
Duvic,M
中科院分区：
文献类型：
--
作者：
Duvic,M
严重银屑病与HIV感染的关联，其失调和破坏人类免疫系统，支持银屑病是免疫介导的疾病的假设。银屑病和卡波西肉瘤的血管生成作为基本的早期发现，可能都是由不同的细胞因子表达或反应性引起的。艾滋病和包括转基因小鼠在内的研究模型为研究免疫系统和特定基因产物在银屑病和其他皮肤病发病机制中的作用提供了新的模型。
The association of severe psoriasis with HIV infection, which dysregulates and destroys the human immune system, supports the hypothesis that psoriasis is an immunologically mediated disease. Psoriasis and Kaposi's sarcoma share angiogenesis as basic early findings and could both be caused by differential cytokine expression or responsiveness. AIDS and research models including transgenic mice offer new models in which to study the role of the immune system and specific gene products in the pathogenesis of psoriasis and other skin diseases.