Quantifying the Extent of Emphysema: Factors Associated with Radiologists' Estimations and Quantitative Indices of Emphysema Severity Using the ECLIPSE Cohort
Quantifying the Extent of Emphysema: Factors Associated with Radiologists' Estimations and Quantitative Indices of Emphysema Severity Using the ECLIPSE Cohort
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DOI：
10.1016/j.acra.2011.01.011
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发表时间：
2011-06-01
影响因子：
4.8
通讯作者：
Coxson, Harvey O.
中科院分区：
文献类型：
--
作者：
Gietema, Hester A.;Mueller, Nestor L.;Coxson, Harvey O.
基本原理和目标：本研究调查了放射科医生在估计肺气肿严重程度时考虑的因素，并评估了低衰减区域的定量计算机断层扫描 (CT) 测量结果。材料和方法：对 1519 名慢性阻塞性肺病 (COPD) 受试者、269 名吸烟者对照和 184 名非吸烟者对照进行 CT 扫描和肺活量测定，这些对照来自 COPD 纵向评估以识别替代终点（日食）研究。使用阈值技术分析 CT 扫描（%
Rationale and Objectives: This study investigated what factors radiologists take into account when estimating emphysema severity and assessed quantitative computed tomography (CT) measurements of low attenuation areas.Materials and Methods: CT scans and spirometry were obtained on 1519 chronic obstructive pulmonary disease (COPD) subjects, 269 smoker controls, and 184 nonsmoker controls from the Evaluation of COPD Longitudinally to Indentify Surrogate Endpoints (ECLIPSE) study. CT scans were analyzed using the threshold technique (%