INTRODUCTION TO SAMPLE-SIZE DETERMINATION AND POWER ANALYSIS FOR CLINICAL-TRIALS

INTRODUCTION TO SAMPLE-SIZE DETERMINATION AND POWER ANALYSIS FOR CLINICAL-TRIALS
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DOI:
10.1016/0197-2456(81)90001-5
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发表时间:
1981-01-01
期刊:
CONTROLLED CLINICAL TRIALS
影响因子:
--
通讯作者:
LACHIN, JM
LACHIN, JM
中科院分区:
其他
文献类型:
--
作者:
LACHIN, JM

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The importance of sample size evaluation in clinical trials is reviewed and a general method is presented from which specific equations are derived for sample size determination or the analysis of power for a wide variety of statistical procedures. The method is discussed and illustrated in relation to the t test, tests for proportions, tests of survival time and tests for correlations as they commonly occur in clinical trials. Most of the specific equations reduce to a simple general form for which tables are presented.