Animal models of reproductive aging: what can they tell us?
Animal models of reproductive aging: what can they tell us?
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DOI：
10.1111/j.1749-6632.2010.05609.x
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发表时间：
2010-01-01
期刊：
影响因子：
--
通讯作者：
Austad, Steven N.
中科院分区：
文献类型：
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作者：
Austad, Steven N.
这篇评论探讨了从实验室研究中可以学到的关于生殖衰老的知识与从实地研究中可以学到的知识之间的关系。实验室研究使研究人员能够分离和分析生殖衰老的详细细胞和分子机制，但是从圈养研究中得出进化推论可能会产生误导。理想的研究将结合联合收割机和实验室的观察和实验。与大多数其他生物现象一样，理解遗传和环境相互作用的本质是理解生殖衰老的核心。
This commentary explores the relationship between what can be learned about reproductive senescence from studies in the laboratory compared with what can be learned from studies in the field. Laboratory studies allow researchers to isolate and analyze detailed cellular and molecular mechanisms of reproductive senescence, however drawing evolutionary inferences from captive studies can be misleading. The ideal study would combine field and laboratory observations and experiments. As with most other biological phenomena, understanding the nature of genetic and environmental interactions is central to understanding of reproductive aging.