THE DISTRIBUTION OF THE SICKLE-CELL TRAIT IN EAST AFRICA AND ELSEWHERE, AND ITS APPARENT RELATIONSHIP TO THE INCIDENCE OF SUBTERTIAN MALARIA
THE DISTRIBUTION OF THE SICKLE-CELL TRAIT IN EAST AFRICA AND ELSEWHERE, AND ITS APPARENT RELATIONSHIP TO THE INCIDENCE OF SUBTERTIAN MALARIA
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DOI：
10.1016/0035-9203(54)90101-7
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发表时间：
1954-01-01
影响因子：
2.2
通讯作者：
ALLISON, AC
中科院分区：
文献类型：
--
作者：
ALLISON, AC
在东非35个不同的土著部落中，镰状细胞特征的发生率被记录下来。在疟疾高度流行的地区，发病率超过10%，但在疟疾仅以流行形式出现的地区，镰状细胞特征的发病率低于10%。镰状细胞病似乎与对疟疾的某种程度的免疫力有关。
The incidence of the sickle-cell trait in East Africa among 35 different native tribes is recorded. In regions where malaria is hyperendemic the incidence is over 10%, but where malaria appears only in epidemic form the incidence of the sickle-cell trait is less than 10%. Sickle-cell condition seems to be correlated with some degree of immunity to malaria.