Quantitative measurement of the palatal mucosa in cleft lip and palate using elastography
Quantitative measurement of the palatal mucosa in cleft lip and palate using elastography
复制标题
使用弹性成像技术定量测量唇裂和腭裂的腭粘膜
DOI：
10.1080/27705781.2022.2058305
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发表时间：
2022
期刊：
影响因子：
--
通讯作者：
K. Maki
中科院分区：
文献类型：
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作者：
Momoko Takakaze;Masahiro Takahashi;K. Maki
目的唇腭裂是颅颌面部最常见的先天性畸形。CLP患者通常在儿童早期进行腭裂手术，这会导致腭粘膜上的瘢痕组织。疤痕组织阻碍了上颌骨的生长。然而，没有研究定量评价腭粘膜的特点。本研究旨在利用弹性成像技术定量评价CLP患者腭裂术后腭粘膜的物理特性。我们还旨在调查腭粘膜的物理特性和使用上颌前牵引治疗（MPA）之间的关联。Materials and MethodsWe招募了57例CLP患者（平均年龄，20.82 ± 3.50岁）和30例对照组无CLP（平均年龄，26.97 ± 2.09岁），并测量了腭粘膜弹性成像的刚度。在与CLP的患者，我们调查了MPA的使用和腭mucosa.ResultsThe硬腭粘膜在患者与CLP之间的关联是显着的僵硬比对照组。此外，在MPA组的腭粘膜是显着僵硬时，调整为裂缝类型与组相比，没有MPA.ConclusionsOur研究结果表明，有特征的差异，在腭粘膜与CLP患者和受试者之间没有CLP和那些与和没有MPA使用。弹性成像可作为一种新的、有效的诊断工具应用于CLP患者的正畸治疗。
PurposeCleft lip and palate (CLP) are the most common congenital abnormalities in the craniofacial region. Patients with CLP usually have palatoplasty in early childhood, which causes scar tissue on the palatal mucosa. Scar tissue prevents growth of the maxilla. However, no studies have quantitatively evaluated the characteristics of the palatal mucosa. This study aimed to quantitatively evaluate the physical characteristics of the palatal mucosa after palatoplasty in patients with CLP using elastography. We also aimed to investigate the association between the physical characteristics of the palatal mucosa and the use of maxillary protraction therapy (MPA).Materials and methodsWe enrolled 57 patients with CLP (mean age, 20.82 ± 3.50 years) and 30 control subjects without CLP (mean age, 26.97 ± 2.09 years) and measured the stiffness of the palatal mucosa using elastography. Among the patients with CLP, we investigated the association between the use of MPA and the stiffness of the palatal mucosa.ResultsThe palatal mucosa in patients with CLP was significantly stiffer than that in control subjects. Moreover, the palatal mucosa in the MPA group was significantly stiffer when adjusted for cleft type compared with the group with no MPA.ConclusionsOur findings suggest that there are characteristic differences in the palatal mucosa between patients with CLP and subjects without CLP and between those with and without MPA use. Elastography could be a new and effective diagnostic tool in orthodontic treatment for patients with CLP.