Protein adsorption on solid surfaces
Protein adsorption on solid surfaces
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DOI：
10.1016/s0958-1669(96)80098-x
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发表时间：
1996-02-01
影响因子：
7.7
通讯作者：
Buijs, J
中科院分区：
文献类型：
--
作者：
Hlady, V;Buijs, J
蛋白质在表面吸附的研究领域似乎一如既往地热门。在过去的一年中，数百篇发表的论文解决了从蛋白质表面相互作用的基本方面到表面血液相容性和蛋白质表面固定化的应用问题。虽然蛋白质吸附过程的某些部分，如动力学和平衡相互作用，可以准确地预测，其他方面，如蛋白质构象变化的程度和速率，仍然有些不确定。对于蛋白质吸附的综合理论来说，整个领域已经成熟。
The research field of protein adsorption on surfaces appears to be as popular as ever. In the past year, several hundred published papers tackled problems ranging from fundamental aspects of protein surface interactions to applied problems of surface blood compatibility and protein surface immobilization. Although some parts of the protein adsorption process, such as kinetics and equilibrium interactions, can be accurately predicted, other aspects, such as the extent and the rate of protein conformational change, are still somewhat uncertain. The whole field is ripe for a comprehensive theory on protein adsorption.