In vivo microcirculation mapping of human skin keloid by 40-MHz ultrafast ultrasound imaging

In vivo microcirculation mapping of human skin keloid by 40-MHz ultrafast ultrasound imaging
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通过 40 MHz 超快超声成像绘制人体皮肤瘢痕疙瘩的体内微循环图

DOI:
10.1109/ultsym.2017.8091991
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发表时间:
2017
期刊:
2017 IEEE International Ultrasonics Symposium (IUS)
影响因子:
--
通讯作者:
Chih
Chih
中科院分区:
--
文献类型:
--
作者:
Pei;Yuan;Chih

文献摘要

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瘢痕疙瘩是一种良性皮肤疾病,其特征是胶原沉积和生长超出了原始伤口的边界。许多关于瘢痕疙瘩的研究表明,瘢痕疙瘩内的血管密度高于正常皮肤,这是组织生理状态的决定因素,对于了解瘢痕疙瘩的发病机制和放射治疗效果也很重要。然而,目前尚缺乏提取瘢痕疙瘩微循环的技术,这促使我们开发了40 MHz超快超高频超声成像技术来可视化瘢痕疙瘩内的微循环。
Keloids are benign dermal disease that are characterized by the collagen deposition and growth beyond the boundaries of the original wound position. Many studies on keloids have showed that the density of blood vessel within keloids is higher than normal skin, which is a determinant of the physiological conditions of the tissue and also important for understanding the pathogenesis and radiotherapy response to keloids. However, the techniques for extracting the microcirculation of keloids are still lacking, which prompts us to develop a 40 MHz ultrafast ultra-high frequency ultrasound imaging to visualize the microcirculation within keloids.