Novel Treatments and Technologies Applied to the Cure of Neuroblastoma.

Novel Treatments and Technologies Applied to the Cure of Neuroblastoma.
复制标题

DOI:
10.3390/children8060482
复制
发表时间:
2021-06-07
期刊:
Children (Basel, Switzerland)
影响因子:
--
通讯作者:
Giuliani S
Giuliani S
中科院分区:
其他
文献类型:
--
作者:
Paraboschi I;Privitera L;Kramer-Marek G;Anderson J;Giuliani S

文献摘要

参考文献

被引文献

相似文献

神经母细胞瘤 (NB) 是儿童期最常见的颅外实体瘤,约占儿科人群所有癌症相关死亡的 15%1。其特点是新生儿临床行为异质,幼儿往往出现不良后果。尽管采取了包括强化化疗、手术、放射治疗和造血干细胞移植在内的积极治疗方案,但患有高危疾病的儿童的总体生存率约为 40-50%2,3。目前正在进行一项研究工作,以增加 NB 的细胞和分子生物学知识,将重要发现转化为新的治疗策略。本综述旨在探讨临床前研究中出现的新治疗方式,为 NB 治疗提供独特的转化机会。
Neuroblastoma (NB) is the most common extracranial solid tumour in childhood, accounting for approximately 15% of all cancer-related deaths in the paediatric population1. It is characterised by heterogeneous clinical behaviour in neonates and often adverse outcomes in toddlers. The overall survival of children with high-risk disease is around 40–50% despite the aggressive treatment protocols consisting of intensive chemotherapy, surgery, radiation therapy and hematopoietic stem cell transplantation2,3. There is an ongoing research effort to increase NB’s cellular and molecular biology knowledge to translate essential findings into novel treatment strategies. This review aims to address new therapeutic modalities emerging from preclinical studies offering a unique translational opportunity for NB treatment.
DOI: 10.1016/j.iotech.2019.07.001
发表时间: 2019-09
期刊: Immuno-oncology technology
影响因子: --
作者:
Chen, Qian;Ci, Tianyuan;Gu, Zhen
通讯作者: Gu, Zhen
DOI: 10.1002/ijc.25140
发表时间: 2010-09-01
影响因子: 6.4
作者:
Croce, Michela;Corrias, Maria Valeria;Ferrini, Silvano
通讯作者: Ferrini, Silvano
DOI: 10.1016/j.jconrel.2009.05.006
发表时间: 2009-09-01
影响因子: 10.8
作者:
Brignole, Chiara;Marimpietri, Danilo;Ponzoni, Mirco
通讯作者: Ponzoni, Mirco
DOI: 10.1007/s00262-007-0317-0
发表时间: 2007-11-01
影响因子: 5.8
作者:
Castriconi, Roberta;Dondero, Alessandra;Corrias, Maria Valeria
通讯作者: Corrias, Maria Valeria
质子束治疗儿童神经母细胞瘤:来自前瞻性 KiProReg 登记处的经验。
DOI: 10.3389/fonc.2020.617506
发表时间: 2020
影响因子: 4.7
作者:
Jazmati D;Butzer S;Hero B;Ahmad Khalil D;Merta J;Bäumer C;Plum G;Fuchs J;Koerber F;Steinmeier T;Peters S;Doyen J;Thole T;Schmidt M;Blase C;Tippelt S;Eggert A;Schwarz R;Simon T;Timmermann B
通讯作者: Timmermann B