Advanced Heart Failure Prevalence, Natural History, and Prognosis
Advanced Heart Failure Prevalence, Natural History, and Prognosis
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DOI：
10.1016/j.hfc.2016.03.001
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发表时间：
2016-07-01
影响因子：
3.4
通讯作者：
Stewart, Garrick C.
中科院分区：
文献类型：
--
作者：
Chaudhry, Sunit-Preet;Stewart, Garrick C.
心力衰竭是一种复杂的临床综合征。这种综合征的自然病程是进行性的。当患者出现治疗难治性心力衰竭的体征和症状时，就存在晚期心力衰竭。最晚期疾病和最差预后的患者可以通过对症状负荷、努力不耐受和心功能不全的反复、综合临床评估来确定。认识到向晚期心力衰竭的转变对于转诊到晚期心脏病项目是必要的。高级心脏病专家可以定制药物治疗，进行风险分层，并评估机械支持，移植或临终姑息治疗方案的候选人资格。
Heart failure is a complex clinical syndrome. The natural history of this syndrome is progressive. Advanced heart failure is present when a patient has signs and symptoms of heart failure that are refractory to therapy. Patients with the most advanced disease and worst prognosis can be identified using iterative, integrated clinical assessment of symptom burden, effort intolerance, and cardiac dysfunction. Recognizing the transition to advanced heart failure is necessary for referral to an advanced heart disease program. Advanced heart disease specialists can tailor medical therapies, perform risk stratification, and evaluate candidacy for mechanical support, transplantation, or end-of-life palliative treatment options.