THE COURSE AND OUTCOME OF PREGNANCY IN WOMEN WITH BRONCHIAL ASTHMA
THE COURSE AND OUTCOME OF PREGNANCY IN WOMEN WITH BRONCHIAL ASTHMA
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支气管哮喘女性妊娠的过程和结果
DOI：
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发表时间：
1972
期刊：
影响因子：
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通讯作者：
T. Bjerkedal
中科院分区：
文献类型：
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作者：
S. Bahna;T. Bjerkedal
长期以来，支气管哮喘患者的后代一直是研究该性状遗传的对象。已经确定的是，一般来说，特应性倾向是遗传的（19）。对于过敏儿童，观察到母亲比父亲更频繁地发生过敏，并且当母亲而不是父亲过敏时，更多的兄弟姐妹受到影响[1]。除了遗传问题的一般特应性倾向，文献没有提供一致的信息，相互影响的怀孕和支气管哮喘。哮喘状况可能会改善，恶化（或在怀孕期间保持不变）（2，9，15，17）。关于哮喘妇女的妊娠过程和妊娠结局，已有报道称胎儿和新生儿死亡率较高，特别是在严重的哮喘病例中（6，11）。Baird（2）认为，与严重哮喘相关的缺氧可导致胎儿死亡或早产。另一方面，Schaefer和Silverman（17）没有观察到对妊娠的有害影响，并指出：“妊娠
The offspring ot patients with bronchial asthma has been tor a long time the subject of study with respect to inheritance of the trait. It has been well established that the atopic tendency, in general, is inherited (19). Eor allergic children, allergy was observed to be more frequent in mothers than in fathers, and more of their siblings were affected when the mother rather than the father was allergic (1). Apart from the question ot inheritance ot the general atopic tendency, the literature does not provide consistent information on the reciprocal etfects of pregnancy and bronchial asthma. The asthmatic condition may ameliorate, deteriorate (ir remain unchanged during pregnancy (2, 9, 15, 17). With respect to the course and outcome of pregnancy in asthmatic women, high foetal and neonatal mortalities have been reported, particularly in severe cases of the disease (6, 11). Baird (2) believes that anoxia associated with severe asthma can lead to foetal death or premature labour. Schaefer and Silverman (17), on the other hand, did not observe deleterious effects on pregnancy and could state: "The pregnant