Phomadecalins A-D and phomapentenone A:: New bioactive metabolites from Phoma sp NRRL 25697, a fungal colonist of Hypoxylon stromata
Phomadecalins A-D and phomapentenone A:: New bioactive metabolites from Phoma sp NRRL 25697, a fungal colonist of Hypoxylon stromata
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DOI：
10.1021/np010519o
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发表时间：
2002-03-01
影响因子：
5.1
通讯作者：
Wicklow, DT
中科院分区：
文献类型：
--
作者：
Che, YS;Gloer, JB;Wicklow, DT
从Phoma sp. 培养物中获得了五种新的天然产物：phomadecalins A-D (1-4) 和phomapentenone A (5)。 (NRRL 25697)，一种从 Hypoxylon sp. 的子座中分离出来的真菌定殖菌。通过一系列一维和二维核磁共振实验阐明了这些化合物的结构。化合物 1-4 显示出抗革兰氏阳性菌的活性。
Five new natural products, phomadecalins A-D (1-4) and phomapentenone A (5), have been obtained from cultures of Phoma sp. (NRRL 25697), a fungal colonist isolated from the stromata of Hypoxylon sp. The structures of these compounds were elucidated through a series of 1D and 2D NMR experiments. Compounds 1-4 display activity against Gram-positive bacteria.