Haemolytic-uraemic syndrome: a 10-year follow-up study of 73 patients.
Haemolytic-uraemic syndrome: a 10-year follow-up study of 73 patients.
复制标题
溶血尿毒症综合征：对 73 名患者进行的 10 年随访研究。
DOI：
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发表时间：
1988
影响因子：
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通讯作者：
L. Monnens
中科院分区：
文献类型：
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作者：
M. De Jong;L. Monnens
长期随访的73例患者患有溶血性尿毒综合征10年后的急性初始疾病。根据Gianantonio提出的标准并根据少尿和/或无尿的持续时间，将患者分为三组。属于第一组的38名患者中有4名（少尿少于7天）血压轻微升高，这是唯一的后遗症。第二组中有两名患者（n = 29，少尿7-14天或无尿少于7天）GFR降低，浓缩能力降低，一些蛋白尿和轻度高血压。其他5例患者有轻微蛋白尿（小于500 mg/24 h），其中1例有轻度高血压。属于第三组的所有六名患者（少尿超过14天或无尿超过7天）都有晚期后遗症：两名患者在初始阶段超过10年后开始血液透析;三名患者的GFR和浓缩能力下降。剩下的唯一一个GFR正常但没有高血压的患者，其注意力集中能力下降。强调了在初始阶段后2年GFR降低的儿童中仔细治疗的重要性。
Long-term follow-up is presented of 73 patients suffering from the haemolytic-uraemic syndrome 10 years after the acute initial illness. The patients were subdivided into three groups, according to the criteria proposed by Gianantonio and based on the duration of oliguria and/or anuria. Four out of 38 patients belonging to the first group (oliguria for less than 7 days) had a slightly increased blood pressure as the only sequela. Two patients out of group two (n = 29, oliguria for 7-14 days or anuria for less than 7 days) had a diminished GFR and a reduced concentrating capacity, some proteinuria, and mild hypertension. Five other patients had slight proteinuria (less than 500 mg/24 h) and one of them a mild hypertension. All six patients belonging to the third group (oliguria for more than 14 days or anuria for more than 7 days) had late sequelae: two started haemodialysis more than 10 years after the initial phase; three have a decreased GFR and concentrating capacity. The unique remaining patient with a normal GFR without hypertension has a decreased concentrating capacity. The importance of careful treatment in children with a decreased GFR 2 years after the initial phase is stressed.